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Pharmacology Pituitary-Hypothalmic System and Thyroid 613b20fa

Which of the following drugs can cause galactorrhea?

A
Omeprazole
B
Metoclopramide
C
Bromocriptine
D
Ranitidine
High-Yield Explanation
Galactorrhea is caused by prolactin secretion. Dopamine normally inhibits the secretion of prolactin. Thus dopamine antagonists can cause hyperprolactinemia leading to galactorrhea. The drugs include: Typical Antipsychotics like Haloperidol Antiemetics like Metoclopramide Dopamine depleter like Reserpine. Drugs stimulating dopamine receptors like Bromocriptine and Cabergoline are used for treatment of Hyperprolactinemia.

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