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Medicine Miscellaneous 61124f01

Cranoitabes (softening of the skull bones) is NOT seen in

A
Osteogenesis imperfect
B
Syphilis
C
Vitamin D deficiency
D
Merasmus
High-Yield Explanation
(A) Osteogenesis imperfecta # Osteogenesis imperfecta causes a generalized decrease in bone mass (osteopenia) and makes the bones brittle. The disorder is frequently associated with blue sclerae, dental abnormalities (dentinogenesis imperfecta), progressive hearing loss, and a positive family history. The most severe forms cause death in utero, at birth, or shortly thereafter. The course of mild and moderate forms is more variable.# Craniotabesis an abnormal softening or thinning of the skull, although normally present in newborns. Seen mostly in occipital bone and posterior part of parietal bone. Bone is soft and has a ping pong ball like feeling on pressing. The term is derived from the Latin words cranium for skull and tabes for wasting. Any condition that affects bone growth, such as rickets (vitamin D deficiency), marasmus, syphilis, or thalassemia present during a time of rapid skull growth can cause craniotabes. It can be a "normal" feature in premature infants.

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