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Pharmacology Central Nervous system 6108aed5

Antipsychotic drug with least extra pyramidal side effect is:

A
Triflupromazine
B
Thioridazine
C
Pimozide
D
Trifluoperazine
High-Yield Explanation
Extrapyramidal motor disturbances ) are intimately linked to the antipsychotic effect, but are more prominent in the high potency compounds and least in thioridazine, clozapine and other atypical antipsychotics. A predominance of lower frequency waves occurs in EEG and arousal response is dampened. However, no consistent effect on sleep architecture has been noted. The disturbed sleep pattern in a psychotic is normalize Ref: KD Tripati 8th ed.

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