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Gynaecology & Obstetrics General 60fe070f

A 24 year old patient has been diagnosed with androgen-insensitivity syndrome. The patient is likely have all of the following signs EXCEPT

A
An XY chromosome complement
B
Menstruation'
C
Female external genitalia
D
Heterosexuality
High-Yield Explanation
A genetic male with androgen-insensitivity (testicular feminization) syndrome has the sexual phenotype of a female. Because there is a genetic defect, the somatic cells do not respond to androgen, and masculinization does not take place prenatally. In adults with androgeninsensitivity syndrome, breast development occurs as a result of testicular estrogen secretion. However, menstruation does not occur because there is no uterus. Individuals with androgen-insensitivity syndrome are usually heterosexual with respect to their sexual phenotype (i.e., they have sexual interest in men).

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