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Pathology Cellular Pathology 60f1ba07

Apoptotic genes regulating programmed cell death type 2, autophagy is:

A
p53
B
BAX
C
BCL-2
D
None of the above
High-Yield Explanation
C i.e.BCL-2Ref: Genetic Home ReferenceExplanation:Autophagy:Autophagy is a process in which a cell eats its own contents (Greek: auto, self; phagy, eating).It involves the delivery of cytoplasmic materials to the lysosome for degradation.Autophagy is an adaptive response that is enhanced during nutrient deprivation, allowing the cell to cannibalize itself to survive.Autophagy can be categorized into three types:Chaperone-mediated autophagy (direct translocation across the lysosomal membrane by chaperone proteins).Microautophagy(inward invagination of lysosomal membrane for delivery).Macroautophagy (hereafter referred to as autophagy), the major form of autophagy involving the sequestration and transportation of portions of cytosol in a double-membrane bound autophagic vacuole (autophagosome).There are many genes and proteins involved in autophagy; BCL2 is one among the notable ones.

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