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Pharmacology CHF, Angina Pectoris and Myocardial Infarction 609ee69b

Which of the following drug can increase the calcium sensitivity of myocytes ?

A
Omapatrilat
B
Levosimendan
C
Milrinone
D
Sacubitril
High-Yield Explanation
Levosimendan Calcium sensitizer which increases the sensitivity of the hea to calcium Positive ionotropic effect on hea without rise in intracellular calcium. Also act as PDE 3 inhibitor. Note : Other drugs in the options are not related to calcium sensitivity of the hea.

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