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Pathology General 607056cf

Fibrin is degraded by-

A
Plasminogen
B
Thromboplastin
C
Plasmin
D
FD
High-Yield Explanation
Ans. is 'c' i.e., Plasmin Fibrinolvtic system o Coagulation must be balanced with fibrinolysis to limit the hemostatic plug to the site of injury. o Injured vascular endothelium secret plasminogen activator that conves inactive plasminogen to active plasmin. o Plasmin breaks down fibrin resulting in production of fibrin degradation products. o Fibrinolytic system is regulated by plasminogen activator inhibitors (PAIs) that are secreted by endothelium.

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