Full 2L QBank
Pathology Haematology 60453cd4

Which of the following is not a myeloproliferative disease -

A
Polycythemia vera
B
Acute myeloid leukemia
C
Chronic myelogenous leukemia
D
Essential thrombocytosis
High-Yield Explanation
The common pathogenic features of myeloproliferative disorders is the presence of mutated, constitutively activated tyrosine kinases or other acquired aberrations in signalling pathways that lead to growth factor independence. It includes CML,POLYCYTHEMIA VERA,ESSENTIAL THROMBOCYTOSIS,primary myelofibrosis. AML is a tumour of haematopoetic progenitors caused by acquired oncogenic mutation that impede differentiation leading to accumulation of immature myeloid blasts in the marrow. Reference :Robbins and Cotran Pathologic basis of disease.South Asia Edition-9 volume 1.page no. 610,616-620

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now