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Pathology Rheumatic Fever 601078de

Aschoff bodies in rheumatic hea disease show all of the following, except:

A
Antischkow cells
B
Epitheloid cells
C
Giant cells
D
Fibrinoid necrosis
High-Yield Explanation
Ascoff bodies constitute: Fibrinoid degeneration Necrosis surrounded by T cells , Plasma cells and macrophages called as Antischow cells (Pathognomic of RF) These macrophages have abundant cytoplasm and central round-to-ovoid nuclei (occasionally binucleate) in which the chromatin condenses into a central, slender, wavy ribbon (hence the designation "caterpillar cells"). Some of the large altered histiocytes become multinucleated to form Aschoff Giant cells.

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