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Pathology General 5ff56de2

In Cicatricial pemphigoid, which antigen is bound by IgG on the epidermal side of the salt split skin technique?

A
XVII collagen
B
Epiligrin
C
Laminin 5
D
BP antigen 1 & 2
High-Yield Explanation
Majority cases of mucous membrane pemphigoid or cicatricial pemphigoid demonstrate IgG directed against antigens on the epidermal side of the salt-split skin, which have been identified as BP 180 or XVII collagen. The antigen present on the dermal side is epiligrin (laminin 5).

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