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Pathology General 5f09fdb6

Staing point of apoptosis for programme cell death is -

A
Activation of endonuclease
B
Release of enzyme
C
Accumulation of calcium
D
None
High-Yield Explanation
Ans. is 'None'o Activation of caspases (not endonuclease) is central in the pathogenesis of apoptosis."A family of proteins known as caspases are typically activated in the early state of apoptosis - Anderson." o After activation of caspases, they (caspases) activate endonuclease.For one answer go ahead with option 'a', because amongst the given option only activation of endonuclease is related to pathogenesis of apoptosis.

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