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Pediatrics Genetics And Genetic Disorders 5ec14c0a

The structural abnormality of chromosome in which one arm is lost and remaining arm is duplicated is called:

A
Ring chromosome
B
Isochromosome
C
Translocation
D
Mutation
High-Yield Explanation
b. Isochromosome(Ref: Nelson's 20/e p 590', Ghai 8/e p 637)Iso-chromosome results when 1 arm of a chromosome is lost and the remaining arm is duplicated or when the axis of division occurs perpendicular to the normal axis of division.

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