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Gynaecology & Obstetrics Pharmacotherapeutic in Obstetrics 5e7c672f

DOC for candidiasis in pregnancy

A
Metronidazole 500mg
B
Tinidazole 500mg
C
Fluconazole
D
Metronidazole 1 gm
High-Yield Explanation
Ans. (c) FluconazoleRef. Shaws 15thed, /: 352CANDIDAL (MONILIAL) VAGINITIS* It is a fungal infection caused by yeast-like microorganisms called Candida or Monilia.* The commonest species causing human disease isCandida albicansClinical Features* Vulval itching is the most common symptom, accompanied by vaginal irritation, dysuria, or both* Thick curdy or flaky vaginal discharge.Diagnosis* Essentially based on clinical findings. But the diagnosis can be confirmed on microscopic examination of a smear of the vaginal discharge treated with 10% KOH solution.* Pap smear shows thick red-stained hyphae and dark red spores.Treatment* A single dose of fluconazole 150 mg has been found to be very effective.* Ideally, both partners should be treated and the underlying predisposing factor corrected to give long- term relief.* Recurrent infection requires fluconazole orally 150 mg every 72 hours for 3 doses.

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