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Pharmacology Endocrinology 5e5c767c

Mechanism of action of propylthiouracil:

A
inhibition of organification of iodine
B
inhibition of oxidation
C
inhibition of coupling
D
all of the above
High-Yield Explanation
Ans. D. All of the aboveThyroid peroxidase enzyme is responsible for oxidation, organification and coupling of thyroid hormone. Thus, propylthiouracil is the inhibitor of thyroid peroxidase enzyme and modulate all the functions.

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