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Microbiology Misc. 5e1c8578

Which of the following group of antifungal drugs acts through squalene epoxidase enzyme?

A
Imidazole and triazole
B
Griseofulvin
C
Polyenes
D
Allylamine and benzylamine
High-Yield Explanation
Ans. D. Allylamine and benzylaminea. Allylamines and benzylaminesb. (terbinafine, butenafine)c. inhibit squalene epoxidase, an early step of ergosterol biosynthesisd. Azolese. Inhibits lanosterol - 14a, demethylase - depletes ergosterol and accumulates aberrant and toxic sterol in the membrane

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