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Biochemistry Vitamins and Minerals 5e08599c

Hydroxylation of proline in collagen requires which of the following:

A
Vitamin C
B
Fe2++
C
a-ketoglutarate
D
All of the above
High-Yield Explanation
Ans. D. All of the aboveProline and Lysine are hydroxylated to form hydroxyl proline and hydroxyl lysine in the presence of enzyme hydroxylase and requires Fe2++' ascorbic acid (Vitamin C), oxygen and a- ketoglutarate.

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