Gynaecology & Obstetrics All India exam 5ce65f8c A major causal factor in some cases of hypogonadism is A Reduced secretion of gonadotropin-releasing hormone (GnRH) B Hypersecretion of pituitary LH and FSH as the result of increased GnRH C Excess secretion of testicular activin by Seoli cells D Failure of the hypothalamus to respond to testosterone High-Yield Explanation Reduced secretion of GnRH will result in extremely low levels of circulating LH and FSH, causing testicular atrophy, as in Kallmann's syndrome.