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Medicine Infection 5cdbbe95

Not true about Clinical course of chicken pox -

A
Skin rash is maculopapular and vesicular in various stages of development
B
Younger children tend to have more vesicles than elders
C
Secondary and tertiary cases in the family have relatively larger number of vesicles
D
Immunocompromised hosts have more chances of visceral complications
High-Yield Explanation
Ans. is 'b' i.e., Younger children tend to have more vesicles than elders Clinical Manifestations of Chicken pox* Clinically, chickenpox presents with a rash, low-grade fever, and malaise, although a few patients develop a prodrome 1-2 days before onset of the exanthem.* In the immunocompetent patient, chickenpox is usually a benign illness associated with lassitude and with body temperatures of 37.8deg-39.4degC (100deg-103degF) of 3-5 days' duration.* The skin lesions--the hallmark of the infection--include maculopapules, vesicles, and scabs in various stages of evolution.* These lesions, which evolve from maculopapules to vesicles over hours to days, appear on the trunk and face and rapidly spread to involve other areas of the body.* Most are small and have an erythematous base with a diameter of 5-10 mm. Successive crops appear over a 2- to 4-day period. Lesions can also be found on the mucosa of the pharynx and/or the vagina.* Younger children tend to have fewer vesicles than older individuals.* Secondary and tertiary cases within families are associated with a relatively large number of vesicles.* Immunocompromised patients--both children and adults, particularly those with leukemia--have lesions (often with a hemorrhagic base) that are more numerous and take longer to heal than those of immunocompetent patients.* Immunocompromised individuals are also at greater risk for visceral complications, which occur in 30-50% of cases and are fatal 15% of the time in the absence of antiviral therapy.

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