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Pharmacology Osteoporosis, Sex Hormones and OCPs 5cb3c8e1

Dr. Shweta decided to add a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women in the gynaecology OPD. Addition of progestin is recommended because the progestin:

A
Blocks the increased risk of myocardial infarction due to estrogen
B
Blocks the increased risk of endometrial carcinoma due to estrogen
C
Reverses vulval atrophy occurring in post menopausal women
D
Enhances the metabolic benefits of estrogen treatment
High-Yield Explanation
Use of estrogen for the treatment or prevention of post-menopausal osteoporosis --> increase risk of breast and endometrial carcinoma. Progesterone is used to decrease the risk of endometrial carcinoma.

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