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Surgery General 5c91aceb

Which of the following condition is associated with an increased risk of developing adenocarcinoma of esophagus?

A
Barret's esophagus
B
Long standing achalasia
C
Corrosive structure
D
Alcohol abuse
High-Yield Explanation
The metaplasia of esophageal squamous epithelium to columnar epithelium (Barrett's esophagus) is a complication of severe reflux esophagitis, and is a risk factor for esophageal adenocarcinoma. Endoscopic biopsy is the gold standard for confirmation of Barrett's esophagus. The hallmark of Barret's esophagus is the presence of mucus secreting goblet cells. Ref: Schwaz's Principles of Surgery, 9th Edition, Chapter 25

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