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Pharmacology General 5bafa521

Which is a selective cyclooxygenase-2 inhibitor ?

A
Ketorolac
B
Tolmetin
C
Nabumitone
D
Oxaprozin
High-Yield Explanation
Ans. is 'c' i.e., Nabumitone o Amongst the given options no drug is selective COX-2 inhibitor. o But Nabumiton is a prefrential COX-2 inhibitor i.e. it has relative COX-2 selectivity --> it inhibits COX-2 more than COX-I. o Other prefrential COX-2 inhibitors are nimesulide and meloxicam.

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