A previously healthy 5-year-old boy presented with a 4-day history of nausea, vomiting, and intermittent abdominal pain. On examination he had mild periorbital edema. A computed tomography scan with contrast demonstrated these findings. What is the diagnosis?
High-Yield Explanation
Answer D. Menetrier's disease The correct answer is Menetrier's disease. This is a rare form of acquired protein-losing enteropathy characterized by giant gastric rugal folds and epithelial hyperplasia and is associated with hypoalbuminemia and edema. This is a pediatric form, which symptomatically resembles the adult-onset type, but can have a benign, self-limited course with spontaneous resolution.