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Medicine Immunology and Rheumatology 5b4b1ea1

Amyloidosis deposition most commonly occurs in:

A
Renal vessels
B
Knee joints
C
Skin
D
Cornea
High-Yield Explanation
Ans. A. Renal vessels* Amyloid is abnormal pathological protein resulting from improper folding of proteins and deposited extracellularly as fibrils and disrupt their normal function.* The most common site of deposition is kidney, followed by, liver, spleen, lymph nodes, adrenals, thyroid, GIT, heart etc.* In systemic amyloidosis, any organ can show deposition of Amyloid. Among all organs, kidneys are most commonly and most seriously get affected by Amyloidosis.

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