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Medicine Disorders of Adrenal Gland 5afc9bce

Best for management of hypoglycemia in a girl child with Congenital adrenal hyperplasia?

A
Betamethasone
B
Beclomethasone
C
Budesonide
D
Hydrocoisone
High-Yield Explanation
* Most common type of CAH (21 hydroxylase deficiency) presents with hypoglycemia with hypotension and virilization. Hydrocoisone injection after bih will help in stabiizing the child by increasing blood sugar and increasing salt absorbtion from the kidney. * Methylprednisolone and dexamethasone have negligible mineralocoicoid effects. Therefore, if the patient is hypovolemic, hyponatremic, or hyperkalemic, large dosages of hydrocoisone are preferred because of its mineralocoicoid effect.

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