Bilateral pulseless disease in upper limbs is caused by -

Answer is 'a' i.e. Aooaeritis "The diagnosis of Takayasu's aeritis should be suspected strongly in a young women who develops a decrease or absence of peripheral pulses, discrepancies in blood pressure and aerial bruits" - Harrison Aooaeritis or Takavasu's ds. is an inflammatory & stenotic disease of the medium and large-sized aeries with a strong predilection for the aoic arch and its branches (therefore also k/a aoic arch syndrome). Narrowing of the lumen of the involved vessels occur with or without thrombosis, leading to symptoms of vascular compromise. Subclan aery is the most commonly involved vessel, leading to loss or weakening of pulses (thus also k/a pulseless ds.) It is mostly seen in adolescent girls and young women. It is more common in Asia.