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Pharmacology Targeted Anticancer Drugs and Immunosuppressants 5ac2201f

A widely used drug that suppresses cellular immunity, inhibits prostaglandin and leukotriene synthesis and increases the catabolism of IgG antibody is:

A
Cyclophosphamide
B
Prednisone
C
Cyclosporine
D
Infliximab
High-Yield Explanation
Glucocoicoids are powerful immunosuppressants. These inhibit both cellular and humoral immunity by: * Decreasing the recruitment of immune cells. * Catabolism of immunoglobulins. * Inhibiting the enzyme phospholipase A2 resulting in decreased production of PGs, LTs and TXs.

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