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Pediatrics General 5a9479fc

Which of the following statements about 21 alpha hydroxylase deficiency is false?

A
Most common cause of Congenital Adrenal Hyperplasia (CAH) in children
B
Affected females present with ambiguous genitalia
C
Affected males present with precocious pubey
D
Hypokalemic alkalosis is seen
High-Yield Explanation
Hyperkalemia is seen in this case.Deficiency of 21 hydroxylase results in manifestations of aldosterone deficiency (salt wasting), loss of sodium (hyponatremia), increase in potassium (hyperkalemia). Ref: OP Ghai 6th Edition, Page 490;Harrison 17th Edition, Page 2267; Nelson 18th Edition, Page 2360- 2365

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