Full 2L QBank
Pathology General 5a875e8c

Which of the following selectin is expressed in both platelets and endothelium?

A
Selectin P
B
Selectin L
C
Selectin E
D
None of the above
High-Yield Explanation
The adhesion of leukocytes to endothelial cells is mediated by complementary adhesion molecules on the two cell types whose expression is enhanced by secreted proteins called cytokines. Cytokines are secreted by cells in tissues in response to microbes and other injurious agents, thus ensuring that leukocytes are recruited to the tissues where these stimuli are present. The initial rolling interactions are mediated by a family of proteins called selectins. There are three types of selectins: one expressed on leukocytes (L-selectin), one on endothelium (E-selectin), and one in platelets and on endothelium (P-selectin). Ref: Robbins 8th edition, Chapter 2.

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now