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Pharmacology General 5a6fd395

Which of the following agents is not associated with Hypehermia

A
Amphetamines
B
MAO inhibitors
C
Atropine
D
Alcohol
High-Yield Explanation
Ans. is 'c' i.e., Alcohol o Amphetamines, MAO inhibitors and anticholinergic drugs (atropine) can cause hypehemia syndromes. Causes of Hypehermia syndromes HEATSTROKE Exeional : Exercise in higher-than-normal heat and/or humidity Nonexeional : Anticholinergic, including antihistamines : antiparkinsonian drugs; diuretics; phenothizines DRUG-INDUCED HYPEHERMIA Amhetamines, cocaine, phencyclidine (PCP) methylenodioxymethamphetamine (MDMA "estasy"), lyserigc acid diethylamide (ISD), salicylates, lithium, anticholinergics. sympathomimetis NEUROLEPTICMALIGNANT SYNDROME Phenothiazines; butyrophenones, including haloperidol and bronperidol : fluoxetine; loxapine; tricyclic dibenzodiazepam, metociopramide; domperidone; thiothixene; molindone; withdrawal of dopaminergic agents. SEROTONINSYNDROME Selective serotonin reuptake inhibitors (S SRI), monoamine oxidase inhibitors (MAOIs), tricyclic antidepresant : MALIGNANT HYPER THERMIA Inhalational anesthetics, succinylcholine EIVDOCRINOPATHY Thyrotoxicosis, pheochromocytoma CENTRAL NERVOUS SYSTEM DAMAGE Cerebral hemorrhage, status epilepticus, hypothalmic injury

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