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Pathology General 5a63e7e7

Tadpole cells comma shaped cells on histopathology are seen in -

A
Trichoepithelioma
B
Spideroma
C
Rhabdomyosarcoma
D
Histiocytoma
High-Yield Explanation
Ans. is 'c' i.e., Rhabdomyosarcoma Histology of rhabdomvosarcoma o The diagnostic cell of rhabdomyosarcoma is rhabdomyoblast. o Rhabdomyoblast contains eccentric eosinophilic granular cytoplasm rich in thick and thin filaments. o The rhabdomyoblasts may be ? i) Round Elongated Tadpole or Strap cells. o It has three variants i) Embryonal Alveolar iii) Pleomorphic o Rhabdomyoblasts are positive for desmin, MYOD1 and Myogenin.

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