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Ophthalmology Lid 5a421690

Chalazion oflid is -

A
Caseous necrosis
B
Chronic nonspecific inflammation
C
Chronic lipogranulomatous inflammation
D
Liposarcoma
High-Yield Explanation
Ans. is 'c' i.e., Chronic lipogranulomatous inflammation Chalaziono Chalazion is chronic non-infective (non-suppurative) lipogranulomatous inflammation of sebaceous glands called meibomian glands.o It results from obstruction of a meibomian gland duct.3 Extravasated lipid material produces a surrounding chronic lipogranulomatous inflammation.o Obstruction is induced by low grade infection that causes proliferation of meibomian gland duct epithelium and infiltration of the wall of ducts.o Patients present with painless, non-tender swelling of the lid. Signs of acute inflammation are not present.o Swelling is slightly away from lid margin.o Occasionally, it may present on the intermarginal strip, i.e. marginal chalazion.o Often chalazion slowly increases in size to become very large and causes blurred vision from induced astigmatism (due to compression on cornea) or eversion of the punctum. Rarely, complete resolution may occur.o Recurrence may occur in seborrhoeic dermatitis, acne rosacea and malignant change.o Secondary malignancy caused by chalagion is Meibomian gland adenocarcinoma (sebaceous cell carcinoma). Secondary infection may cause hordeolum internum.

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