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Pharmacology Autonomic nervous system 5a20c477

The most impoant action of beta-blockers in glaucoma is :

A
Membrane stabilizing effect
B
Refinal neuron protecting effect
C
Decrease in the production of aqueous humor
D
Pupillary constriction
High-Yield Explanation
Ref: KD Tripathi pharmacology 7th edition (page.no: 144) Topical b blockers are one of the first-line drug for glaucoma In contrast to miotics, the b blockers do not affect pupil size, the tone of ciliary muscle or outflow facility, but lower i.o.t. by reducing aqueous formation. This probably results from down-regulation of adenylyl cyclase due to b 2 receptor blockade in the ciliary epithelium and a secondary effect due to a reduction in ocular blood flow.

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