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Biochemistry Enzymes 5a1d86c6

Myocardial infarction is associated with increased of

A
CPK
B
CPK-MM
C
CPK-MB
D
CPK - BB
High-Yield Explanation
C. i.e. (CPK - MB) (III - U. Satyanarayan 3rd) (599- Rana Shinde 7th)CPK exists as three isoenzyme - Each isoenzyme is a dimmer composed of two subunits - M (muscle) or B (brain) or bothIso enzymeSubunitTissue of originCPK,BBBraincpk2MBHeartCPK3MMSkeletal muscle* CPK2- MB is the earliest reliable indication of myocardial infarction* Troponins are more sensitive and specific*** CPK - NOT found in RB cells and it level is not affected by haemolysis* Normal value - 4 - 60 IU/L (at 37degC)

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