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Pharmacology General 595b0421

The anaesthetic agent which should NOT be used in a patient with previous history of halothane induces hepatitis is:

A
Methoxyflurane
B
Sevoflurane
C
Isoflurane
D
Ketamine
High-Yield Explanation
Halothane causes idiosyncratic type liver injury. It is genetically predisposed. Jaundice is usually noted 7-10 days after the exposure. Because of the cross reaction between halothane and methoxyflurane, it should not be used in a patient with halothane reaction. Ref: Harrison, Edition-18, Page-2564

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