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Pathology General 5944612f

Fractalkine is also called --------------.

A
CXCL8
B
RANTES
C
MCP-1
D
CX3CL 1
High-Yield Explanation
CX3 C chemokines contain three amino acids between the first two cysteines. The only known member of this class is called fractalkine (CX3 CL1). This chemokine exists in two  forms:  a  cell  surface-bound protein induced on endothelial cells by inflammatory cytokines that promotes strong adhesion of monocytes and T cells, and a soluble form, derived by proteolysis of the membrane-bound protein, that has potent chemoattractant activity for the same cells. Reference-Robbins BASIC PATHOLOGY 10th edition pg-172

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