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Physiology Heart, Circulation, and Blood 592e1d69

Dicumarol is a drug that impairs the utilization of vitamin K by the liver. Dicumarol therapy, therefore, would decrease the plasma concentration of which of the following procoagulants

A
Prothrombin
B
Fibrinogen
C
Antihemopilic factor (factor VIII)
D
Ac - globulin (factor V)
High-Yield Explanation
Ans. (a) ProthrombinRef: Ganong, 25th ed/p.567Factor II is also called Prothrombin. It is a vitamin K dependent factorWarfarin - acts by inhibiting Vitamin K Epoxide reductase (VKORC1)

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