Not true about Alport's syndrome-

Ans. is 'b' i.e., Autosomal dominant o The autosomal dominant form also exist, but it is very rare. Thus, among the given options, it is the best answer,o Other three options are classical features of Alport's syndrome.Alport's syndromeo Alport's syndrome is a type of hereditary nephritis characterized by -i) Glomerulonephritis progressing to chronic renal failure.ii) Nerve deafnessiii) Eye defects -lenticonus, lens dislocation, posterior cataract, corneal dystrophy,o Most commonly it is inherited as X-linked form.o Rare autosomal - recessive and autosomal-dominant pedigrees also exist.Pathogenesiso There is defective GBM synthesis because of production of abnormal collagen type IV underlies the renal lesions,o The defect is caused by mutation in the gene encoding a-chain of collagen type IV.