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Biochemistry Glucose Transpo 588513c5

Which of the following is defective in renal glycosuria:

A
GLUT- 1
B
GLUT- 2
C
SGLT- 1
D
SGLT- 2
High-Yield Explanation
Renal Glycosuria (also called Familial Renal Glucosuria or Glycosuria ) Blood glucose is normal, But still Glucose appears in urine. It is due to defect/mutation in SGLT-2, which is major glucose transpoer (90% glucose reabsorption) present in kidneys for the reabsorption and transpo of Glucose (see fig below). Mutation in SGLT-1 (10% glucose reabsoption) leads to glucose-galactose malabsorption

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