The commonest site of liquefactive necrosis is

NECROSIS ■ Enzymatic degradation of a cell resulting from exogenous injury. ■ Characterized by enzymatic digestion and protein denaturation, with the release of intracellular components. ■ Morphologically occurs as coagulative (heart, liver, kidney), liquefactive (brain), caseous (tuberculosis), fat (pancreas), fibrinoid (blood vessels), or gangrenous (limbs, GI tract). ■ Kidney infarct exhibiting coagulative necrosis will be seen with loss of nuclei and clumping of cytoplasm but with preservation of basic outlines of glomerular and tubular architecture. ■ Liquefactive necrosis in the kidney can be caused by fungal infection, which will be seen filled with white cells and cellular debris, creating a renal abscess that obliterates the normal architecture.