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Medicine Miscellaneous 586d7603

Diabetes insipidus treatment includes all EXCEPT:

A
Metformin
B
Chlorpropamide
C
Desmopressin
D
Carbamazepine
High-Yield Explanation
(A) Metformin # Desmopressin: Desmopressin acetate is the treatment of choice for central diabetes in insipidus associated with pregnancy or the puerperium, since desmopressin is resistant to degradation by the circulating vasopressinase> It is usually given intranasally (100 pg./mL solution) every 12-24 hours as needed for thirst and polyuria.> It may be administered via metered-dose nasal inhaler containing 0.1 ml/spray or via a plastic calibrated tube.> Patients are started with 0.05-0.1 ml_ every 12-24 hours, and the dose is then individualized according to response.

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