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Surgery Anatomy & Physiology (Oesophagus) 581bd1d1

Lower esophageal sphincter tone is due to

A
Vasoactive intestinal peptide
B
Nitrous oxide
C
Acetylcholine
D
Pancreatic polypeptide
High-Yield Explanation
Ans. (c) AcetylcholineRef: Bailey & Love 26th ed. / 988There are two types of control of LES via the Myenteric plexus:* Excitatory (cholinergic) ganglionic neurons* Inhibitory (nitric oxide) ganglionic neuronsFunctionally, inhibitory neurons mediate Deglutitive lower esophageal sphincter (LES) relaxation and the sequential propagation of peristalsis.

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