A 26-year-old female presents for ante natal visit. She has a history of abortion in last pregnancy due to neural tube defect in the fetus. What is the amount of folic acid that should be prescribed to this female?

Ans. (D) 4000 micrograms per day(Ref: Williams Obstetrics 24th/e p 1104; Nelson 19th/e p2001)All women of childbearing age and who are capable of becoming pregnant should take 0.4 mg (=400 mcg) of folic acid daily.If pregnancy is planned in high-risk women (previously affected child), supplementation should be started with 4 mg (= 4000 microgram) of folic acid daily, beginning 1 month before the time of the planned conception.