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Psychiatry Substance abuse 57b490bf

Which of the following is used to maintain abstinence in alcohol dependence

A
Naltrexone
B
Clonidine
C
Disulfiram
D
Naloxone
High-Yield Explanation
Naltrexone (oral opioid receptor antagonist) probably interferes with alcohol-induced reinforcement by blocking opioid receptors., helping in maintaining alcohol abstinence. Ref: Sho textbook of Psychiatry by Niraj Ahuja 7th editon, page 42. Disulfiram also helps in alcohol abstinence but through its unpleasant reactions to alcohol intake.

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