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Medicine Drugs 57405075

All of the following can cause SLE like syndrome except -

A
INH
B
Penicillin
C
Hydralazine
D
Sulphonamide
High-Yield Explanation
Ans. is 'b' i.e., Penicillin Drug induce SLEAppearance of SLE like symptoms in association with intake of certain drugs.Common symptoms are fever, malaise, arthritis or intense arthralgias/ myalgias, serositis and or rash.Some special points to note are -It is predominant in CaucasiansQIt has less female predilection than SLE.It rarely involves kidneys or brain Q.It is rarely associated with anti-Ds DNAQ.It is commonly associated with antibodies to histones Q.It usually resolves over several weeksQ after discontinuation of the offending medication.

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