All of the following are causes of 'propoionate sho stature' EXCEPT?
High-Yield Explanation
Osteogenesis imperfecta is one of the causes of dispropoionate sho stature, where the limbs are mainly involved, as compared to trunk. Osteogenesis imperfecta: MC cause of multiple fractures in childhood. Autosomal dominant Defected type 1 collagen. C/F: Bone shape- not maintained. Deformed bones, fractures in different areas & different stages of healing. Blue sclera Deafness Dentigerous imperfecta Rx: Gene therapy