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All of the following statements about amlodipine are true except:

A
It acts by conversion to an active metabolite in the liver
B
It has a very large volume of distribution
C
It undergoes very little first pass metabolism and possesses high and consistent oral bioavailability
D
It has a very long elimination half life
High-Yield Explanation
(Ref: KDT 6/e p531) Amlodipine is the longest acting DHP. It undergoes little first pass metabolism and is distributed widely. metabolites of amlodipine are inactive.
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