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Pathology Aplastic Anemia 56e02dff

Diagnostic criteria of pure red cell aplasia (PRCA) includes all of the following, except:

A
Severe anemia
B
Reticulocyte count < 1%
C
Normocellular marrow
D
Thrombocytopenia
High-Yield Explanation
Pure red cell aplasia: Selective depletion of erythroid precursors in bone marrow with consequent severe normocytic normochromic anemia & reticulocytopenia. Diagnostic criteria for pure red cell aplasia are: Giant normoblasts in bone marrow Severe anemia Reticulocyte count < 1% Normocellular marrow with mature erythroblasts <0.5%.

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