Pharmacology Other topics and Adverse effects 56ddbfd1

Which of the following metabolic reactions require vitami B12 but not folate?

Conversion of malonic acid to succinic acid

Conversion of homocysteine to methionine

Conversion of serine to glycine

Thymidylate synthesis

High-Yield Explanation

(Ref: KDT 6/e p588) Conversion of malonic acid to succinic acid requires vitamin B12 but not folate. This reaction is required for myelin formation and deficiency of B12 is responsible for demyelination.

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Which of the following metabolic reactions require vitami B12 but not folate?

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