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Anatomy Other topics and Adverse effects 56b56f84

All of the following antihypeensive drugs increase plasma rein activity except :

A
Clonidine
B
Hydralazine
C
Nifedipine
D
Captopril
High-Yield Explanation
(Ref:KDT 6/e p546) Plasma renin activity is increased by reflex increase in sympathetic discharge. Clonidine decreases central sympathetic outflow and thus will decease the plasma renin activity. Vsodilators and ACE inhibitors result in reflex increase in plasma renin activity.

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