Prion disease is caused by

ref Robbins 9/e p1281 Prion diseases are caused by misfolded forms of the prion protein, also known as PrP. ... The human forms of prion disease are most often the names Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gesmann-Straussler-Scheinker syndrome (GSS), kuru and variably protease-sensitive prionopathy (VPSPr